Melissa (MyStreet)/Affiliation

Aaron
When the two were young, Melissa had better control over her emotions than Aaron. This caused Aaron to yell a lot and he still had a hard time facing her. Eventually, they patched up their relationship at the end of MyStreet Season 3 and MyStreet: Holiday Special.

Derek and Rachel
Melissa has not be shown to directly "love" her parents, they also act on a business level. As shown in a flashback, Rachel knows Melissa well and Derek does too. Of course, at the end of the day, they do love each other.

Aphmau
Aphmau was always nice to Melissa, but she was at first wary of Aphmau. Melissa came to visit Aphmau to get to know her but she hadn't warmed up completely. In MyStreet: Aphmau's Year, Melissa has warmed to Aphmau, even showing an interest in Aaron's and her relationship.

The Romaeves
Melissa treats them like business partners as they are the Lycan's business partner.

Aphmau and Aaron's Friends
Melissa has exactly shown any feeling towards Aphmau and Aaron's friends, but she does find their competitive spirits good for her show.

Michi
Melissa does dislike Michi as she butted into her private business and tried to be a star.